Cold Spring Harbor Laboratory (CSHL) invites applications for the position of Postdoctoral Research Fellow in Chemical Biology to work on a project involving the synthesis of antisense oligonucleotides (ASOs). You will be part of a collaborative research effort between the laboratories of Professor Mike Wigler and Professor John E. Moses and based in the new $75 million Center for Therapeutic Research (CTR).
The exciting research project will involve the design, synthesis, and biological evaluation of a series of novel cell penetrating ASOs for targeting pathogens and treating disorders of gene expression.
We are looking for a highly motivated, experienced, and interactive synthetic chemist to join the team. You will have the ability to grow with the organization and make essential contributions to the collaborative research environment. The ideal candidate must have synthetic chemistry expertise, with proven experience in synthesis of peptide–, peptide nucleic acid–, and/or nucleic acid synthesis.
You will also need to be skilled in protein and nucleic acid purification and characterization. You will also be adept with analytical techniques, NMR, HPLC, and Mass Spectrometry.
EDUCATION: Successful applicants will possess a PhD degree or equivalent in Synthetic Organic Chemistry or Chemical Biology.
EXPERIENCE: Two years of research experience is preferred. Prior experience in synthetic organic chemistry is essential, and also the synthesis of peptides, peptide nucleic acids, and/or nucleic acids. Preferably, you will have a working knowledge of click chemistry, drug discovery and biological assays—experience with analytical techniques, including NMR and Mass Spectrometry.
Skills: The successful candidate should possess excellent organizational, analytical, and communication skills, maintaining data spreadsheets, will be willing to take the initiative, and will be able to work effectively and productively in a team-oriented environment while maintaining a strong sense of integrity.
Interested candidates should apply online to position # 02806-R using the following link:
https://cshl.peopleadmin.com/postings/17589. Please include a CV and publication list, a statement of research interest and contact information of three references.
We offer a highly collaborative social and scientific environment as well as a competitive salary and benefits.
Cold Spring Harbor Laboratory is a world-renowned research and educational institution with programs in cancer, neuroscience, plant biology, genomics and bioinformatics. The Laboratory is recognized internationally for its excellence in research and educational activities.
For more information about CSHL, please visit us at www.cshl.edu
CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status.